TriangleHEALTH PROFESSIONAL · SOURCE READING
Treatment Options for Moderately Advanced Lesions of the Lip
Source: Lip and Oral Cavity Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: May 14, 2025 · Captured 2026-09-09.
Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.
Context: Treatment of Stage III Lip and Oral Cavity Cancer
These lesions, including those involving bone, nerves, and lymph nodes, generally require a combination of surgery and radiation therapy.
Treatment options for stage III advanced lesions of the lip include:
Surgery using a variety of approaches, the choice of which is dependent on the size and location of the lesion and the need for reconstruction.
Radiation therapy using a variety of techniques, including external-beam radiation therapy (EBRT) with or without brachytherapy, the choice of which is dictated by the size and location of the lesion.
Clinical trials for advanced tumors evaluating the use of chemotherapy preoperatively, before radiation therapy, as adjuvant therapy after surgery, or as part of combined modality therapy are appropriate.[3-6,8-10]
Superfractionated radiation therapy (under clinical evaluation).[11]
Source links and citations
Publication references
Read the original reference and check its publication notices.
Preserved source evidence · Not medical advice