HEALTH PROFESSIONAL · SOURCE READING

Treatment Options for Moderately Advanced Lesions of the Buccal Mucosa

Source: Lip and Oral Cavity Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: May 14, 2025 · Captured 2026-09-09.

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Context: Treatment of Stage III Lip and Oral Cavity Cancer

Treatment options for stage III advanced lesions of the buccal mucosa include:

Radical surgical resection alone.

Radiation therapy alone.

Surgical resection plus radiation therapy, generally postoperative.

Clinical trials for advanced tumors evaluating the use of chemotherapy preoperatively, before radiation therapy, as adjuvant therapy after surgery, or as part of combined modality therapy are appropriate.[3-6,8-10,12]

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Preserved source evidence · Not medical advice