TriangleHEALTH PROFESSIONAL · SOURCE READING
Treatment Options for Small Lesions of the Floor of the Mouth
Source: Lip and Oral Cavity Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: May 14, 2025 · Captured 2026-09-09.
Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.
Context: Treatment of Stage II Lip and Oral Cavity Cancer
Treatment options for stage II small lesions of the floor of the mouth include:
Surgery is often used for patients with small T2 lesions (≤3 cm) if the lesion is attached to the periosteum.
Radiation therapy is often used to treat patients with small T2 lesions (≤3 cm) if the lesion encroaches on the tongue.
Surgery and radiation therapy are alternative methods of treatment for patients with large T2 lesions (>3 cm), the choice of which depends primarily on the expected extent of disability from surgery.
External-beam radiation therapy with or without interstitial radiation therapy should be considered postoperatively for larger lesions.
Preserved source evidence · Not medical advice