TriangleFOR PATIENTS · SOURCE READING
Treatment of Stage IV Metastatic and Recurrent Lip and Oral Cavity Cancer
Source: Lip and Oral Cavity Cancer Treatment (PDQ®)–Patient Version, National Cancer Institute.
Source updated: May 16, 2025 · Captured 2026-09-09.
Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.
Learn about the treatments listed below in the Treatment Option Overview.
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Treatment of metastatic (IVC) and recurrent lip and oral cavity cancer may include:
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surgery, if radiation therapy was used before
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surgery and/or radiation therapy, if surgery was used before
immunotherapy (nivolumab or pembrolizumab)
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Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.
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Preserved source evidence · Independent clinical review pending · Not medical advice