Chemotherapy

Source: Late Effects of Treatment for Childhood Cancer (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: April 14, 2025 · Captured 2026-09-09.

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The association of chemotherapy alone with xerostomia remains controversial.[18]

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Only one study of pediatric patients demonstrated an excess risk (OR, 12.32; 95% CI, 2.1–74.4) of decreased stimulated saliva flow rates among patients treated with cyclophosphamide. However, an increase in dental caries was not noted and patient-reported xerostomia was not evaluated.[6]

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Publication references

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PubMed 20237805 · Original source
PubMed 21523736 · Original source

Preserved source evidence · Not medical advice