Conventional cardiovascular conditions

Various cancer treatment exposures may also directly or indirectly influence the development of hypertension, diabetes mellitus, and dyslipidemia.

These conditions remain important among cancer survivors, as they do in the general population, in that they are independent risk factors in the development of cardiomyopathy, ischemic heart disease, and cerebrovascular disease.[8,69-72]

Childhood cancer survivors should be closely monitored for the development of these cardiovascular conditions because they represent potentially modifiable targets for intervention.

Related conditions such as obesity and various endocrinopathies (e.g., hypothyroidism, hypogonadism, growth hormone deficiency) that may be more common among subsets of childhood cancer survivors also need to be monitored. If these conditions are untreated/uncontrolled, they may be associated with a metabolic profile that increases cardiovascular risk.[9] For more information, see the Risk prediction for cardiovascular diseases section.