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← Late Effects of Treatment for Childhood Cancer (PDQ®)

HEALTH PROFESSIONAL · SOURCE READING

Radiation therapy

Source: Late Effects of Treatment for Childhood Cancer (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: April 14, 2025 · Captured 2026-09-09.

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Context: Late Effects of the Urinary System / Therapy-Related Bladder Complications

Pelvic radiation therapy is also associated with an increased risk of hemorrhagic cystitis that may be either acute or chronic in presentation.

The risk of radiation-induced hemorrhagic cystitis is greatest among survivors treated with radiation doses of more than 30 Gy to the whole bladder or more than 60 Gy to a portion of the bladder.[44]

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Long-term bladder fibrosis and contracture may result as sequelae from hemorrhagic cystitis or radiation therapy.[44]

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Preserved source evidence · Not medical advice