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Treatment Options for Metastatic and Recurrent Laryngeal Cancer
Source: Laryngeal Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: May 14, 2025 · Captured 2026-09-09.
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Context: Treatment of Metastatic and Recurrent Laryngeal Cancer
Treatment options for metastatic and recurrent laryngeal cancer include:
Surgery [1] and/or radiation therapy. Salvage is possible for failures of surgery alone or of radiation therapy alone, and further surgery [1] and/or radiation therapy should be attempted, as indicated. Selected patients may be candidates for partial laryngectomy after high-dose radiation therapy has failed.[2]
Radiation therapy. Re-irradiation for laryngeal salvage following radiation therapy failure has resulted in long-term survival in a small number of patients; it may be considered for small recurrences after radiation therapy, especially in patients who refuse or are not candidates for laryngectomy.[3]
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Chemotherapy.
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Immunotherapy.
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Clinical trials for patients whose disease does not respond to combined radiation therapy and surgery.
For more information, see the Treatment Option Overview for Laryngeal Cancer section.
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Preserved source evidence · Not medical advice