TriangleFOR PATIENTS · SOURCE READING
Treatment of Stage III Renal Cell Cancer
Source: Renal Cell Cancer Treatment (PDQ®)–Patient Version, National Cancer Institute.
Source updated: May 12, 2025 · Captured 2026-09-09.
Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.
Treatment of stage III renal cell cancer may include:
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radical nephrectomy
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arterial embolization to reduce blood loss during surgery followed by radical nephrectomy
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radical nephrectomy followed by pembrolizumab or sunitinib
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external beam radiation therapy or arterial embolization as palliative therapy to relieve symptoms and improve the quality of life
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external beam radiation therapy before or after surgery (radical nephrectomy), for certain people with more extensive tumors
Learn more about these treatments in the Treatment Option Overview.
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Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.
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Preserved source evidence · Independent clinical review pending · Not medical advice