HEALTH PROFESSIONAL · SOURCE READING

Radiation therapy

Source: Kaposi Sarcoma Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: May 7, 2025 · Captured 2026-09-09.

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Context: Treatment of Classic and Endemic Kaposi Sarcoma / Treatment Options for Advanced Classic and Endemic Kaposi Sarcoma

Modest doses can be effective in controlling widespread skin disease. The type of radiation (i.e., photon vs. electron) and fields used must be tailored to suit the distribution of disease in the individual patient.[1] Radiation therapy options include:

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Extended-field EBRT.

For disease limited to areas distal to the knee, subtotal-skin EBRT directed to skin below the umbilicus.

For disease that extends above the knee, total-skin EBRT.EBRT used in this manner gave long-term results that were superior to those obtained with radiation therapy administered to successive individual lesions as they appeared.[4]

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For extensive disease, EBRT 4 Gy given once weekly for 6 to 8 consecutive weeks, and subtotal- or total-skin radiation therapy.

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Preserved source evidence · Not medical advice