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← Kaposi Sarcoma

HEALTH PROFESSIONAL · SOURCE READING

Bortezomib

Source: Kaposi Sarcoma Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: May 7, 2025 · Captured 2026-09-09.

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Context: Treatment of AIDS-Associated Kaposi Sarcoma / Treatment Options for AIDS-Associated Kaposi Sarcoma / Biological and targeted therapy

Evidence (bortezomib):

Bortezomib was evaluated in a small phase I dose-escalation study of 17 patients with AIDS-associated KS. Patients received bortezomib IV on days 1, 8, and 15 of 28-day cycles.[25]

Source links and citations

Bortezomib was evaluated in a small phase I dose-escalation study of 17 patients with AIDS-associated KS. Patients received bortezomib IV on days 1, 8, and 15 of 28-day cycles.[25]

Bortezomib was relatively well tolerated and led to a PR in 60% of all evaluable patients. Among those receiving the highest bortezomib dose, 83% of patients had a PR and 17% had stable disease.

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Preserved source evidence · Not medical advice