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← Kaposi Sarcoma

HEALTH PROFESSIONAL · SOURCE READING

Other chemotherapy agents

Source: Kaposi Sarcoma Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: May 7, 2025 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.

Context: Treatment of Classic and Endemic Kaposi Sarcoma / Treatment Options for Advanced Classic and Endemic Kaposi Sarcoma / Chemotherapy

Single-agent vinblastine [13-16], oral etoposide [17-19], and gemcitabine [20-22] have all shown good activity in classic and AIDS-associated KS.

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Evidence (other chemotherapy agents):

A phase III trial included 65 patients with classic KS. Patients were randomly assigned to receive either oral etoposide or vinblastine.[18]

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A phase III trial included 65 patients with classic KS. Patients were randomly assigned to receive either oral etoposide or vinblastine.[18]

Response rates were relatively high and did not significantly differ (58% for patients who received PLD and 74% for patients who received paclitaxel).[18][Level of evidence B3]

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Preserved source evidence · Not medical advice