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← Intraocular (Uveal) Melanoma

HEALTH PROFESSIONAL · SOURCE READING

Treatment Options for Ciliary Body Melanoma

Source: Intraocular (Uveal) Melanoma Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: May 16, 2025 · Captured 2026-09-09.

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Context: Treatment of Ciliary Body Melanoma

There are several options for management of ciliary body melanoma. All of them are reported from case series.[Level of evidence C3] The choice of therapy, however, depends on many factors.

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Treatment options for ciliary body melanoma include:

Plaque radiation therapy. Local control rates are high, but treatment is associated with a high incidence of secondary cataract.[4,5]

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External-beam, charged-particle radiation therapy. This approach is offered at specialized referral centers. It requires careful patient cooperation, with voluntary fixation of gaze.[6-8]

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Local tumor resection. This option is mainly suitable for selected ciliary body or anterior choroidal tumors with smaller basal dimension and greater thickness.[9,10]

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Enucleation. This option is generally reserved for large melanomas when regaining useful vision is unlikely. It is also indicated in the presence of intractable secondary glaucoma and extraocular extension.[5,8]

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Preserved source evidence · Not medical advice