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Treatment Options for Iris Melanoma
Source: Intraocular (Uveal) Melanoma Treatment (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: May 16, 2025 · Captured 2026-09-09.
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Context: Treatment of Iris Melanoma
Treatment options for iris melanoma include:
Observation with careful follow-up. This option is used in asymptomatic patients with stable lesions; follow-up includes serial photography.[3]
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Local resection. This option is used when progressive and pronounced growth is documented.[2]
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Enucleation. This option is used if the tumor is not amenable to local resection because of diffuse involvement of the iris, involvement of more than 50% of the iris and anterior chamber angle, intractable glaucoma, or extraocular extension.[7]
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Plaque radiation therapy. This option is offered as an alternative for large, diffuse, surgically nonresectable lesions of the iris.[8]
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Preserved source evidence · Not medical advice