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← Hypopharyngeal Cancer

HEALTH PROFESSIONAL · SOURCE READING

Treatment Options for Metastatic and Recurrent Hypopharyngeal Cancer

Source: Hypopharyngeal Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: May 14, 2025 · Captured 2026-09-09.

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Context: Treatment of Metastatic and Recurrent Hypopharyngeal Cancer

Treatment options for metastatic and recurrent hypopharyngeal cancer include:

Surgical resection if radiation therapy fails and if technically feasible.[1]

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Radiation therapy, if not previously used in curative doses that preclude further treatment, if surgery fails.

Surgical salvage, if technically feasible, when surgery fails.

Chemotherapy for metastatic disease.[2]

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Immunotherapy.[3-11]

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Immunotherapy.[3-11]

Pembrolizumab.

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Immunotherapy.[3-11]

Nivolumab.

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Clinical trials evaluating the use of chemotherapy should be considered.[12]

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Preserved source evidence · Not medical advice