TriangleHEALTH PROFESSIONAL · SOURCE READING
Treatment Options Under Clinical Evaluation for Childhood NUT Carcinoma
Source: Childhood NUT Carcinoma Treatment (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: August 7, 2024 · Captured 2026-09-09.
Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.
Information about National Cancer Institute (NCI)–supported clinical trials can be found on the NCI website. For information about clinical trials sponsored by other organizations, see the ClinicalTrials.gov website.
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The following are examples of national and/or institutional clinical trials that are currently being conducted:
NCT05019716 (Testing the Safety and Efficacy of the Addition of A New Anti-cancer Drug, ZEN003694, to Chemotherapy Treatment [Etoposide and Cisplatin] for Adult and Pediatric Patients [Aged 12–17 Years] With NUT Carcinoma): This phase I/II trial will determine the maximum tolerated dose of the BET bromodomain inhibitor ZEN-3694 added to cisplatin and etoposide to treat patients with NUT carcinoma. This trial will also evaluate the efficacy of this treatment regimen.
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NCT05372640 (Testing the Safety and Efficacy of the Combination of Two Anticancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients [Aged 12–17 years] With Metastatic or Unresectable NUT Carcinoma, Breast Cancer, and Other Solid Tumors): This phase I trial will determine the maximum tolerated dose of the BET bromodomain inhibitor ZEN003694 given with abemaciclib to treat patients with metastatic or unresectable NUT carcinoma, breast cancer, or other solid tumors.
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Studies cited in this source section
Source citation is not a determination that a study applies to you.
Preserved source evidence · Not medical advice