Treatment of tumors caused by childhood MEN2B syndrome

Source: Childhood Multiple Endocrine Neoplasia Type 2 (MEN2) Syndrome, National Cancer Institute.

Source updated: Not stated in this source · Captured 2026-09-09.

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Context: Types of treatment for children with tumors caused by MEN2 syndrome

There is an increased risk of medullary thyroid cancer, an aggressive form of thyroid cancer, in people with MEN2B syndrome. Infants with MEN2B syndrome and certain changes in the RET gene usually have surgery to remove the thyroid to lessen the chance cancer will form. Treatment is also given for pheochromocytoma and other conditions as needed.

Children with MEN2B syndrome who have medullary thyroid cancer may be treated with:

surgery to remove the thyroid

targeted therapy with vandetanib or selpercatinib

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Preserved source evidence · Independent clinical review pending · Not medical advice