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← Childhood Multiple Endocrine Neoplasia (MEN) Syndromes

FOR PATIENTS · SOURCE READING

Treatment of tumors caused by childhood MEN2A syndrome

Source: Childhood Multiple Endocrine Neoplasia Type 2 (MEN2) Syndrome, National Cancer Institute.

Source updated: Not stated in this source · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.

NCI patient article for the named subtype within this topic Source-defined subtype article; do not apply its treatment text to every subtype in the umbrella topic.

Context: Types of treatment for children with tumors caused by MEN2 syndrome

There is an increased risk of medullary thyroid cancer, an aggressive form of thyroid cancer, in people with MEN2A syndrome. Children with MEN2A syndrome and certain changes in the RET gene usually have surgery to remove the thyroid before age 5 years to lessen the chance cancer will form or spread. Treatment is also given for pheochromocytoma and hyperparathyroidism as needed.

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Treatment of medullary thyroid cancer in children who have MEN2A syndrome may include:

surgery to remove the thyroid

targeted therapy with selpercatinib

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Preserved source evidence · Independent clinical review pending · Not medical advice