HEALTH PROFESSIONAL · SOURCE READING
Treatment of Hairy Cell Leukemia
Source: Hairy Cell Leukemia Treatment (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: February 21, 2025 · Captured 2026-09-09.
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Hairy cell leukemia is highly treatable but rarely cured. Because it is easily controlled, many patients have prolonged survival with the use of sequential therapies. The decision to treat is based on signs of disease progression, including any of the following factors:
Cytopenias (especially if symptomatic).
Increasing splenomegaly.
The presence of other, usually infectious, complications.
If the patient is asymptomatic and if blood counts are maintained in an acceptable range, therapy may not be needed.[1]
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