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HEALTH PROFESSIONAL · SOURCE READING

Bendamustine with rituximab

Source: Hairy Cell Leukemia Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: February 21, 2025 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.

Context: Treatment of Hairy Cell Leukemia / Treatment Options for Hairy Cell Leukemia

Evidence (bendamustine with rituximab):

A phase II study evaluated 12 patients with relapsed or refractory disease, three of whom were negative for BRAF variants. Patients received the combination of bendamustine and rituximab.[30]

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A phase II study evaluated 12 patients with relapsed or refractory disease, three of whom were negative for BRAF variants. Patients received the combination of bendamustine and rituximab.[30]

The overall response rate was 100%, and the complete remission rate was 50%.[30][Level of evidence C3]

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Preserved source evidence · Not medical advice