TriangleFOR PATIENTS · SOURCE READING
High-risk Metastatic Gestational Trophoblastic Neoplasia
Source: Gestational Trophoblastic Disease Treatment (PDQ®)–Patient Version, National Cancer Institute.
Source updated: February 25, 2022 · Captured 2026-09-09.
Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.
Context: Treatment Options for Gestational Trophoblastic Disease / Gestational Trophoblastic Neoplasia
Treatment of high-risk metastatic gestational trophoblastic neoplasia (invasive mole or choriocarcinoma) may include the following:
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Combination chemotherapy.
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Intrathecal chemotherapy and radiation therapy to the brain (for cancer that has spread to the lung, to keep it from spreading to the brain).
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High-dose chemotherapy or intrathecal chemotherapy and/or radiation therapy to the brain (for cancer that has spread to the brain).
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Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.
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Preserved source evidence · Independent clinical review pending · Not medical advice