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← Gastrointestinal Stromal Tumors

HEALTH PROFESSIONAL · SOURCE READING

Pazopanib

Source: Gastrointestinal Stromal Tumors Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: December 13, 2024 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.

Context: Treatment of Metastatic or Recurrent GISTs / Treatment Options for Metastatic or Recurrent GISTs / Additional TKI therapy options

Pazopanib inhibits VEGF signaling and showed modest PFS benefit when compared to best supportive care in a small phase II trial of patients with imatinib- and sunitinib-resistant GISTs. However, pazopanib had a high rate of toxicity.[46]

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