HEALTH PROFESSIONAL · SOURCE READING

Chemotherapy and radiation therapy

Source: Endometrial Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: May 14, 2025 · Captured 2026-09-09.

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Context: Treatment of Stage III, Stage IV, and Recurrent Endometrial Cancer / Treatment Options for Stage III, Stage IV, and Recurrent Endometrial Cancer

Patients with inoperable disease caused by tumor that extends to the pelvic wall may be treated with a combination of chemotherapy and radiation therapy. The usual approach for radiation therapy is a combination of intracavitary and external-beam radiation therapy (EBRT).[17,18]

Source links and citations

For patients with localized recurrences (pelvic and para-aortic lymph nodes) or distant metastases in selected sites, radiation therapy may be an effective palliative therapy. Pelvic radiation therapy may be curative in patients with pure vaginal recurrence when no previous radiation therapy has been used.

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