HEALTH PROFESSIONAL · SOURCE READING
Treatment Options for Liver Metastasis
Source: Colon Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: February 12, 2025 · Captured 2026-09-09.
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Context: Treatment of Stage IV and Recurrent Colon Cancer
Approximately 50% of colon cancer patients will be diagnosed with hepatic metastases, either at the time of initial presentation or because of disease recurrence. Although only a small proportion of patients with hepatic metastases are candidates for surgical resection, advances in tumor ablation techniques and in both regional and systemic chemotherapy administration provide for several treatment options. These include:
Surgery.
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Neoadjuvant chemotherapy.
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Local ablation.
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Adjuvant chemotherapy.
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Intra-arterial chemotherapy.
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