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Targeted therapy
Source: Chronic Myeloid Leukemia Treatment (PDQ®)–Patient Version, National Cancer Institute.
Source updated: April 9, 2025 · Captured 2026-09-09.
Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.
Context: Treatment Option Overview / The following types of treatment are used:
Targeted therapy is a type of treatment that uses drugs or other substances to identify and attack specific cancer cells.
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Tyrosine kinase inhibitor therapy blocks the enzyme tyrosine kinase that causes stem cells to develop into more white blood cells (blasts) than the body needs.Tyrosine kinase inhibitors used to treat CML include:Having bariatric surgery may block some absorption of oral tyrosine kinase inhibitors, limiting their effectiveness.
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Tyrosine kinase inhibitor therapy blocks the enzyme tyrosine kinase that causes stem cells to develop into more white blood cells (blasts) than the body needs.Tyrosine kinase inhibitors used to treat CML include:Having bariatric surgery may block some absorption of oral tyrosine kinase inhibitors, limiting their effectiveness.
asciminib
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Tyrosine kinase inhibitor therapy blocks the enzyme tyrosine kinase that causes stem cells to develop into more white blood cells (blasts) than the body needs.Tyrosine kinase inhibitors used to treat CML include:Having bariatric surgery may block some absorption of oral tyrosine kinase inhibitors, limiting their effectiveness.
imatinib mesylate
Tyrosine kinase inhibitor therapy blocks the enzyme tyrosine kinase that causes stem cells to develop into more white blood cells (blasts) than the body needs.Tyrosine kinase inhibitors used to treat CML include:Having bariatric surgery may block some absorption of oral tyrosine kinase inhibitors, limiting their effectiveness.
dasatinib
Tyrosine kinase inhibitor therapy blocks the enzyme tyrosine kinase that causes stem cells to develop into more white blood cells (blasts) than the body needs.Tyrosine kinase inhibitors used to treat CML include:Having bariatric surgery may block some absorption of oral tyrosine kinase inhibitors, limiting their effectiveness.
nilotinib
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Tyrosine kinase inhibitor therapy blocks the enzyme tyrosine kinase that causes stem cells to develop into more white blood cells (blasts) than the body needs.Tyrosine kinase inhibitors used to treat CML include:Having bariatric surgery may block some absorption of oral tyrosine kinase inhibitors, limiting their effectiveness.
bosutinib
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Learn more about Targeted Therapy to Treat Cancer and Drugs Approved for Chronic Myeloid Leukemia.
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Preserved source evidence · Independent clinical review pending · Not medical advice