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← Childhood Acute Promyelocytic Leukemia

HEALTH PROFESSIONAL · SOURCE READING

Gemtuzumab Ozogamicin

Source: Childhood Acute Promyelocytic Leukemia Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: June 14, 2024 · Captured 2026-09-09.

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Context: Treatment of Recurrent APL

In one trial, the use of gemtuzumab ozogamicin, an anti-CD33/calicheamicin antibody-drug conjugate, as a single agent resulted in a molecular remission rate of 91% (9 of 11 patients) after two doses and a molecular remission rate of 100% (13 of 13 patients) after three doses. These results demonstrate excellent activity of this agent in patients with relapsed APL.[19]

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