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← Childhood Soft Tissue Sarcoma

FOR PATIENTS · SOURCE READING

Chemotherapy

Source: Childhood Soft Tissue Sarcoma (PDQ®)–Patient Version, National Cancer Institute.

Source updated: May 9, 2025 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.

Context: Types of treatment for childhood soft tissue sarcoma

Chemotherapy (also called chemo) uses drugs to stop the growth of cancer cells. Chemotherapy either kills the cancer cells or stops them from dividing. Chemotherapy may be given alone or with other types of treatment, such as radiation therapy.

For children with soft tissue sarcoma, chemotherapy is taken by mouth or injected into a vein. When given this way, the drugs enter the bloodstream to reach cancer cells throughout the body.

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The way the chemotherapy is given depends on the type of soft tissue sarcoma being treated. Some types of soft tissue sarcoma may respond to treatment with chemotherapy.

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Chemotherapy that may be used alone or in combination includes:

cisplatin

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cyclophosphamide

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dactinomycin

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doxorubicin

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hydroxyurea

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ifosfamide

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methotrexate

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vinblastine

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vincristine

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vinorelbine

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Other chemotherapy drugs not listed here may also be used.

Learn more about how chemotherapy works, how it is given, common side effects, and more at Chemotherapy to Treat Cancer.

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Preserved source evidence · Independent clinical review pending · Not medical advice