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Infantile Fibrosarcoma
Source: Childhood Soft Tissue Sarcoma Treatment (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: April 21, 2025 · Captured 2026-09-09.
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Context: Treatment of Fibroblastic and Myofibroblastic Tumors
There are two distinct types of fibrosarcoma in children and adolescents, as follows:
Infantile fibrosarcoma is a malignant fibroblastic tumor usually characterized by ETV6::NTRK3 gene fusions.
Adult-type fibrosarcoma is composed of monomorphic fibroblastic tumor cells. Some of the genomic features of adult-type fibrosarcoma have been recently described.[81]
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These are two distinct pathological diagnoses and require different treatments.
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Preserved source evidence · Not medical advice