HEALTH PROFESSIONAL · SOURCE READING

Genomic alterations

Source: Childhood Soft Tissue Sarcoma Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: April 21, 2025 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.

Context: Treatment of Tumors of Uncertain Differentiation / Epithelioid Sarcoma

Epithelioid sarcoma is characterized by inactivation of the SMARCB1 gene, which is present in both conventional and proximal types of epithelioid sarcoma.[55] This abnormality leads to increased dependence on EZH2 and tumor formation.[56]

Source links and citations

Publication references

Read the original reference and check its publication notices.

PubMed 19033866 · Original source
PubMed 23620515 · Original source

Preserved source evidence · Not medical advice