Surgery

Surgical excision of local recurrence.

Surgical excision of local recurrence.

An Italian review of 73 patients with recurrent malignant peripheral nerve sheath tumors found that most relapses were local.[3][Level of evidence C1]

Surgical excision of local recurrence. › An Italian review of 73 patients with recurrent malignant peripheral nerve sheath tumors found that most relapses were local.[3][Level of evidence C1]

Multivariate analysis showed that the factors associated with improved survival were no tumor invasiveness at initial diagnosis (stage T1), time of recurrence more than 12 months after initial diagnosis, and achievement of a second complete response with surgical removal of the recurrence(s).

Surgical excision of local recurrence. › An Italian review of 73 patients with recurrent malignant peripheral nerve sheath tumors found that most relapses were local.[3][Level of evidence C1]

Only 15.8% of patients who had complete surgical excisions of local recurrence(s) were alive at 5 years.

Surgical excision of isolated pulmonary occurrence.

Surgical excision of isolated pulmonary occurrence.

Pulmonary metastasectomy may achieve prolonged disease control for some patients.[4]

Surgical excision of isolated pulmonary occurrence. › Pulmonary metastasectomy may achieve prolonged disease control for some patients.[4]

A large, retrospective analysis showed that patients with recurrent soft tissue sarcoma and isolated local relapse had a better prognosis and resection of pulmonary metastases improved the probability of survival.[5]

Surgical excision of isolated pulmonary occurrence. › Pulmonary metastasectomy may achieve prolonged disease control for some patients.[4]

In 31 children and adolescents younger than 23 years with pulmonary metastases from synovial sarcoma, complete resection of lung metastases appeared to prolong survival when compared with ten other patients who were not candidates for metastasectomy.[6][Level of evidence C1]

Surgical excision of local recurrence followed by radiation therapy or brachytherapy (if no previous radiation therapy was given).

Limb amputation (only for some children with extremity sarcomas that have already received radiation therapy).