HEALTH PROFESSIONAL · SOURCE READING

Surgery

Source: Childhood Ovarian Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: March 3, 2025 · Captured 2026-09-09.

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Context: Childhood Sex Cord–Stromal Tumors / Childhood Sertoli-Leydig Cell Tumors / Treatment and outcome of childhood Sertoli-Leydig cell tumors

Surgery is the primary treatment for Sertoli-Leydig cell tumors and is the only treatment for low-stage disease (FIGO stage IA). The event-free survival rate for these patients is approximately 100%.[2][Level of evidence C1] However, up to 10% of patients may develop metachronous contralateral tumors, particularly in the context of underlying DICER1 germline pathogenic variants.[28]

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