Treatment of Childhood Epithelial Ovarian Neoplasia

Treatment options for nonmalignant childhood epithelial ovarian neoplasia include the following:

Treatment of epithelial ovarian neoplasia is based on stage and histology. Most pediatric and adolescent patients have stage I disease. In the TREP study,[3] of the eight patients with benign tumors, seven patients had stage I disease, and one patient had stage III disease. Of the eight patients with borderline tumors, three patients had stage I disease, and five patients had stage III disease (based on washings and omental implants). All 16 patients were treated with surgery alone. At the time of the report, 15 patients were alive without disease; the one death was not from ovarian cancer.

Treatment options for childhood malignant ovarian epithelial cancer include the following:

Treatment of malignant ovarian epithelial cancer is stage-related and follows adult protocols, which may include surgery and chemotherapy. For more information, see Ovarian Epithelial, Fallopian Tube, and Primary Peritoneal Cancer Treatment.