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← Childhood Non-Hodgkin Lymphoma

FOR PATIENTS · SOURCE READING

Treatment of recurrent or refractory diffuse large B-cell lymphoma

Source: Childhood Non-Hodgkin Lymphoma Treatment (PDQ®)–Patient Version, National Cancer Institute.

Source updated: May 9, 2025 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.

Context: Treatment Options for Childhood Non-Hodgkin Lymphoma / Diffuse large B-cell lymphoma

For information about the treatments listed below, see Treatment Option Overview.

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Treatment of recurrent or refractory diffuse large B-cell lymphoma may include:

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combination chemotherapy with or without targeted therapy (rituximab)

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targeted therapy (rituximab), combination chemotherapy, and dexamethasone

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stem cell transplant with the patient's own cells or cells from a donor

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CAR T-cell therapy

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Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.

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Preserved source evidence · Independent clinical review pending · Not medical advice