TriangleFOR PATIENTS · SOURCE READING
Treatment of Childhood Melanoma
Source: Childhood Melanoma Treatment (PDQ®)–Patient Version, National Cancer Institute.
Source updated: October 18, 2021 · Captured 2026-09-09.
Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.
For information about the treatments listed below, see the Treatment Option Overview section.
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Treatment of newly diagnosed melanoma that has not spread to lymph nodes or other parts of the body includes the following:
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Surgery to remove the tumor and some healthy tissue around it.
Treatment of newly diagnosed melanoma that has spread to nearby lymph nodes includes the following:
Surgery to remove the tumor and the lymph nodes with cancer.
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Immunotherapy with immune checkpoint inhibitors (pembrolizumab, ipilimumab, or nivolumab).
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Targeted therapy with BRAF inhibitors (vemurafenib, dabrafenib, or encorafenib) alone or with MEK inhibitors (trametinib or binimetinib).
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Treatment of newly diagnosed melanoma that has spread to other parts of the body may include the following:
Immunotherapy (ipilimumab).
A clinical trial of an oral targeted therapy drug (dabrafenib) in children and adolescents.
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Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.
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Preserved source evidence · Independent clinical review pending · Not medical advice