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Treatment of Childhood Melanoma
Source: Childhood Melanoma Treatment (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: April 3, 2025 · Captured 2026-09-09.
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The European Cooperative Study Group for Pediatric Rare Tumors within the PARTNER project (Paediatric Rare Tumours Network - European Registry) has published recommendations for the diagnosis and treatment of children and adolescents with cutaneous melanoma. Some of these recommendations have been incorporated and summarized in the sections below.[1] A Children's Oncology Group–led panel of experts from different specialties have also developed recommendations for the diagnostic evaluation and surgical management of cutaneous melanomas, atypical Spitz tumors, and non-Spitz melanocytic tumors.[2]
Treatment options for childhood melanoma include the following:
Surgery and, in certain cases, sentinel lymph node biopsy and lymph node dissection.
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Immune checkpoint inhibitors or BRAF/MEK inhibitors.
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