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← Childhood Hodgkin Lymphoma

HEALTH PROFESSIONAL · SOURCE READING

Classical Hodgkin lymphoma, low-risk disease

Source: Childhood Hodgkin Lymphoma Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: April 16, 2025 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.

Context: Treatment of Newly Diagnosed Children and Adolescents With Hodgkin Lymphoma / Accepted Risk-Adapted Treatment Strategies

Table 7 summarizes the results of treatment approaches used for pediatric patients with low-risk Hodgkin lymphoma.

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Table 7. Treatment Approaches for Pediatric Patients With Low-Risk Hodgkin Lymphoma
Chemotherapy (No. of Cycles)aRadiation (Gy)StageNo. of PatientsEvent-Free Survival Rate (No. of Years of Follow-up)Survival Rate (No. of Years of Follow-up)
CS = clinical stage; IFRT = involved-field radiation therapy; N/A = not applicable; No. = number.
aFor more information about the chemotherapy regimens, see Table 6.
bIncluded patients with nodular lymphocyte-predominant Hodgkin lymphoma.
OEPA (2) [24]IFRT (20–35)I, IIA28194% (5)N/A
None11397% (5)
ABVD [78]IFRT (21–35)I–IV20985% (5)97% (5)
ABVE (2-4)b [66]IFRT (25.5)IA, IIA, IIIA1, without bulky disease5191% (6)98% (6)
AV-PC [44]NoneIA, IIA, without bulky disease27879.9% (4)99.6% (4)
Response-based IFRT (21)
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Preserved source evidence · Not medical advice