HEALTH PROFESSIONAL · SOURCE READING

Treatment of Progressive or Recurrent Childhood Craniopharyngioma

Source: Childhood Craniopharyngioma Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: November 26, 2024 · Captured 2026-09-09.

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Progression or recurrence of craniopharyngioma varies according to the type of up-front therapy, but it has been reported to be between 20% (patients who received a subtotal resection and radiation therapy) and 90% (patients who received a subtotal resection without radiation therapy).[1-3]

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Treatment options for recurrent childhood craniopharyngioma include the following:

Surgery.

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Surgery

Radiation therapy, including radiosurgery.

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Radiation therapy, including radiosurgery

Intracystic therapy (intracavitary instillation of radioactive phosphorus P 32 [32P] or bleomycin for those with cystic recurrences, where these agents are available).

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Intracystic therapy (intracavitary instillation of radioactive phosphorus P 32 [32P] or bleomycin for those with cystic recurrences, where these agents are available)

Systemic targeted therapy.

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Systemic targeted therapy

Observation.

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Observation

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Surgery →Radiation Therapy →Intracystic Therapy →Systemic and Targeted Therapy →Observation →Treatment Options Under Clinical Evaluation →

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Preserved source evidence · Not medical advice