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← Childhood Astrocytomas, Other Gliomas, and Glioneuronal/Neuronal Tumors

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Treatment of progressive or recurrent childhood low-grade glioma, astrocytoma, neuronal, or glioneuronal tumors

Source: Childhood Glioma (Including Astrocytoma), National Cancer Institute.

Source updated: May 10, 2024 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.

Childhood glioma, astrocytoma, glioneuronal, and neuronal tumors can be progressive or recurrent. They most often come back in the same area but can spread to other areas in the brain. Before more cancer treatment is given, imaging tests, biopsy, or surgery are done to find out if there is cancer, how much there is, and the grade.

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Treatment of progressive or recurrent childhood low-grade glioma, astrocytoma, glioneuronal, and neuronal tumors may include:

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a second surgery to remove the tumor

radiation therapy (including conformal radiation therapy), if radiation therapy was not used when the tumor was first diagnosed

chemotherapy, if the tumor progressed or recurred where it cannot be removed by surgery

targeted therapy (bevacizumab) with or without chemotherapy

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targeted therapy (everolimus or sirolimus)

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targeted therapy (dabrafenib and trametinib)

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To learn more about these treatments, see Types of treatment for childhood glioma (including astrocytoma).

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Preserved source evidence · Independent clinical review pending · Not medical advice