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← Childhood Astrocytomas, Other Gliomas, and Glioneuronal/Neuronal Tumors

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Treatment of recurrent childhood high-grade gliomas

Source: Childhood Glioma (Including Astrocytoma), National Cancer Institute.

Source updated: May 10, 2024 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.

Treatment of recurrent childhood high-grade glioma may include:

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second surgery depending on tumor type, location, and length of time between treatment and recurrence

radiation therapy

targeted therapy (dabrafenib and trametinib)

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a clinical trial of targeted therapy

a clinical trial of immunotherapy

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To learn more about these treatments, see Types of treatment for childhood glioma (including astrocytoma).

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Preserved source evidence · Independent clinical review pending · Not medical advice