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← Childhood Acute Lymphoblastic Leukemia

HEALTH PROFESSIONAL · SOURCE READING

Asparaginase

Source: Childhood Acute Lymphoblastic Leukemia Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: April 21, 2025 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.

Context: Treatment of Newly Diagnosed Childhood ALL / Standard Induction Treatment Options for Newly Diagnosed ALL / Remission induction chemotherapy

Several forms of asparaginase have been used in the treatment of children with ALL, including the following:

Pegaspargase (PEG-asparaginase).

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Calaspargase pegol.

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Asparaginase Erwinia chrysanthemi (Erwinia L-asparaginase).

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Native Escherichia coli (E. coli) L-asparaginase (unavailable in the United States, but still available in other countries).

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Pegaspargase (PEG-asparaginase) →Calaspargase pegol →Asparaginase Erwinia chrysanthemi (Erwinia L-asparaginase) →

Preserved source evidence · Not medical advice