Toxicity of CNS-Directed Therapy

Source: Childhood Acute Lymphoblastic Leukemia Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: April 21, 2025 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.

Context: Central Nervous System (CNS)-Directed Therapy for Childhood ALL

Toxic effects of CNS-directed therapy for childhood ALL can be acute and subacute or late developing. For more information, see the Late Effects of the Central Nervous System section in Late Effects of Treatment for Childhood Cancer.

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Late Effects of the Central Nervous System

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Acute and subacute toxicities →Late-developing toxicities →

Preserved source evidence · Not medical advice