Sex

Source: Childhood Acute Lymphoblastic Leukemia Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: April 21, 2025 · Captured 2026-09-09.

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Context: Risk-Based Treatment Assignment / Prognostic Factors Affecting Risk-Based Treatment / Patient and clinical disease characteristics

In some studies, the prognosis for girls with ALL is slightly better than it is for boys with ALL.[79-81] One reason is the occurrence of testicular relapses among boys, but boys also appear to be at increased risk of bone marrow and CNS relapse for reasons that are not well understood.[79-81] While some reports describe outcomes for boys as closely approaching those of girls,[23,57,82] larger clinical trial experiences and national data continue to show somewhat lower survival rates for boys.[22,33,83,84]

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