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Treatment Option Overview for Cervical Cancer
Source: Cervical Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: May 13, 2025 · Captured 2026-09-09.
Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.
Patterns-of-care studies clearly demonstrate the negative prognostic effect of increasing tumor volume and spread pattern.[1] Treatment, therefore, may vary within each stage as the individual stages are currently defined by Fédération Internationale de Gynécologie et d’Obstétrique (FIGO).
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| Stage (FIGO Staging Criteria) | Treatment Options |
|---|---|
| FIGO = Fédération Internationale de Gynécologie et d’Obstétrique. | |
| In situ carcinoma of the cervix (this stage is not recognized by FIGO) | Conization |
| Hysterectomy for postreproductive patients | |
| Internal radiation therapy for medically inoperable patients | |
| Stage IA cervical cancer | Conization |
| Total hysterectomy | |
| Modified radical hysterectomy with lymphadenectomy | |
| Radical trachelectomy | |
| Intracavitary radiation therapy | |
| Stages IB, IIA cervical cancer | Radiation therapy with concomitant chemotherapy |
| Radical hysterectomy and bilateral pelvic lymphadenectomy with or without total pelvic radiation therapy plus chemotherapy | |
| Radical trachelectomy | |
| Radiation therapy alone | |
| Immunotherapy | |
| Neoadjuvant chemotherapy (under clinical evaluation) | |
| Intensity-modulated radiation therapy (under clinical evaluation) | |
| Stages IIB, III, and IVA cervical cancer | Radiation therapy with concomitant chemotherapy |
| Interstitial brachytherapy | |
| Neoadjuvant chemotherapy | |
| Immunotherapy | |
| Stage IVB and recurrent cervical cancer | Immunotherapy |
| Radiation therapy and chemotherapy | |
| Palliative chemotherapy and other systemic therapy | |
| Pelvic exenteration | |
| Phase I and phase II clinical trials of new anticancer drugs | |
Source links and citations
- FIGO Staging Criteria
- Conization
- Hysterectomy for postreproductive patients
- Internal radiation therapy for medically inoperable patients
- Conization
- Total hysterectomy
- Modified radical hysterectomy with lymphadenectomy
- Radical trachelectomy
- Intracavitary radiation therapy
- Radiation therapy with concomitant chemotherapy
- Radical hysterectomy and bilateral pelvic lymphadenectomy
- Radical trachelectomy
- Radiation therapy alone
- Immunotherapy
- Neoadjuvant chemotherapy
- Intensity-modulated radiation therapy
- Radiation therapy with concomitant chemotherapy
- Interstitial brachytherapy
- Neoadjuvant chemotherapy
- Immunotherapy
- Immunotherapy
- Radiation therapy and chemotherapy
- Palliative chemotherapy and other systemic therapy
- Pelvic exenteration
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