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HEALTH PROFESSIONAL · SOURCE READING

Surgical Treatment for Breast Cancer

Source: Breast Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: April 25, 2025 · Captured 2026-09-09.

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Operable breast cancer requires a multimodal approach to treatment. After the presence of a malignancy is confirmed by biopsy, the following surgical treatment options can be discussed with the patient before a therapeutic procedure is selected:

Breast-conserving surgery.

Modified radical mastectomy (removal of the entire breast with axillary dissection of levels I and II) with or without breast reconstruction.

To guide the selection of neoadjuvant or adjuvant therapy, many factors including stage, grade, and molecular status of the tumor (e.g., estrogen receptor [ER], progesterone receptor [PR], human epidermal growth factor type 2 receptor [HER2], or triple-negative status) are considered.[1-5]

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