TriangleHEALTH PROFESSIONAL · SOURCE READING
Stages I, II, and III Triple-Negative Breast Cancer (TNBC)
Source: Breast Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: April 25, 2025 · Captured 2026-09-09.
Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.
Context: Systemic Therapy for Stages I, II, and III Breast Cancer
TNBC is defined as the absence of staining for ER, PR, and HER2. TNBC is insensitive to some of the most effective therapies for patients with breast cancer, including HER2-directed therapy such as trastuzumab and endocrine therapies such as tamoxifen or AIs.
Continue within this section
Preserved source evidence · Not medical advice