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HEALTH PROFESSIONAL · SOURCE READING

Tamoxifen and chemotherapy

Source: Breast Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: April 25, 2025 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.

Context: Systemic Therapy for Stages I, II, and III Breast Cancer / Stages I, II, and III HER2-Negative Hormone Receptor–Positive Breast Cancer / Timing of postoperative chemotherapy

Because of the results of an EBCTCG analysis, the use of tamoxifen in women who received adjuvant chemotherapy does not attenuate the benefit of chemotherapy.[21] However, concurrent use of tamoxifen with chemotherapy is less effective than sequential administration.[44]

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Preserved source evidence · Not medical advice