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HEALTH PROFESSIONAL · SOURCE READING

Radical cystectomy (in rare, highly selected patients with extensive or refractory superficial high-grade tumors)

Source: Bladder Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: May 2, 2025 · Captured 2026-09-09.

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Context: Treatment of Stage 0 Bladder Cancer / Treatment Options for Stage 0 Bladder Cancer

Radical cystectomy is used in selected patients with extensive or refractory superficial tumors,[2,30,31] based on reports that up to 20% of patients with Tis will die of bladder cancer. However, cystectomy (whether segmental or radical) is generally not indicated for patients with Ta or Tis bladder cancer. Patients at high risk of progression, typically those with recurrent high-grade tumors with carcinoma in situ after intravesical therapy with BCG, should consider radical cystectomy.[32-35]

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