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← Aggressive B-Cell Non-Hodgkin Lymphoma

HEALTH PROFESSIONAL · SOURCE READING

Treatment Options for Aggressive, Noncontiguous Stage II/III/IV B-Cell NHL

Source: Aggressive B-Cell Non-Hodgkin Lymphoma Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: May 12, 2025 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.

Context: Treatment of Aggressive, Noncontiguous Stage II/III/IV B-Cell Non-Hodgkin Lymphoma

Treatment options for aggressive, noncontiguous stage II/III/IV B-cell NHL include:

Pola-R-CHP (for National Comprehensive Cancer Network International Prognostic Index [IPI] score of 2 to 5).

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R-CHOP.

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Radiation therapy consolidation to sites of bulky disease (under clinical evaluation).

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Pola-R-CHP →R-CHOP →Radiation therapy consolidation to sites of bulky disease →Bone marrow transplant (BMT) or stem cell transplant (SCT) →Prognostic factors →

Preserved source evidence · Independent clinical review pending · Not medical advice