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← Soft Tissue Sarcoma

HEALTH PROFESSIONAL · SOURCE READING

Surgery and lymphadenectomy

Source: Soft Tissue Sarcoma Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: February 21, 2025 · Captured 2026-09-09.

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Context: Treatment of Advanced Stage III (N1) Soft Tissue Sarcoma / Treatment Options for Advanced Stage III (N1) Soft Tissue Sarcoma

Regional lymph node involvement by soft tissue sarcomas in adults is rare but may occur in some sarcoma types. The sarcoma types that more commonly spread to lymph nodes include:[1]

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High-grade rhabdomyosarcoma.

Vascular sarcomas.

Synovial sarcoma.

High-grade fibrosarcoma.

Clear cell sarcoma.

Epithelioid sarcomas.

Surgical resection and lymphadenectomy with or without postoperative radiation therapy may be indicated for patients with clinically positive lymph nodes.[1]

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Preserved source evidence · Not medical advice