HEALTH PROFESSIONAL · SOURCE READING
Surgery and lymphadenectomy
Source: Soft Tissue Sarcoma Treatment (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: February 21, 2025 · Captured 2026-09-09.
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Regional lymph node involvement by soft tissue sarcomas in adults is rare but may occur in some sarcoma types. The sarcoma types that more commonly spread to lymph nodes include:[1]
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High-grade rhabdomyosarcoma.
Vascular sarcomas.
Synovial sarcoma.
High-grade fibrosarcoma.
Clear cell sarcoma.
Epithelioid sarcomas.
Surgical resection and lymphadenectomy with or without postoperative radiation therapy may be indicated for patients with clinically positive lymph nodes.[1]
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