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Treatment of Stage III Soft Tissue Sarcoma That Has Spread to Lymph Nodes (Advanced)
Source: Soft Tissue Sarcoma Treatment (PDQ®)–Patient Version, National Cancer Institute.
Source updated: June 2, 2023 · Captured 2026-09-09.
Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.
For information about the treatments listed below, see Treatment Option Overview. To learn about the cancer stages, see Stages of Soft Tissue Sarcoma.
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Treatment of stage III soft tissue sarcoma that has spread to lymph nodes (advanced) may include the following:
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Surgery (wide local excision) with lymphadenectomy. Radiation therapy may also be given after surgery.
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Surgery with neoadjuvant therapy (chemotherapy or radiation therapy) or adjuvant therapy (radiation therapy).
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Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.
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Preserved source evidence · Independent clinical review pending · Not medical advice